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L Norton Selected Research

Therapeutics

8/2015Response to dual HER2 blockade in a patient with HER3-mutant metastatic breast cancer.
1/2014Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle.
9/2012Prevention and treatment of pressure ulcers.
5/2008Intent-to-treat analysis of the placebo-controlled trial of letrozole for extended adjuvant therapy in early breast cancer: NCIC CTG MA.17.
5/2005Value of intravenous 6-mercaptopurine during continuation treatment in childhood acute lymphoblastic leukemia and non-Hodgkin's lymphoma: final results of a randomized phase III trial (58881) of the EORTC CLG.
9/2001Circulating HER-2/erbB-2/c-neu (HER-2) extracellular domain as a prognostic factor in patients with metastatic breast cancer: Cancer and Leukemia Group B Study 8662.
5/2001Weekly trastuzumab and paclitaxel therapy for metastatic breast cancer with analysis of efficacy by HER2 immunophenotype and gene amplification.
4/2001Value of high-dose cytarabine during interval therapy of a Berlin-Frankfurt-Munster-based protocol in increased-risk children with acute lymphoblastic leukemia and lymphoblastic lymphoma: results of the European Organization for Research and Treatment of Cancer 58881 randomized phase III trial.
1/2001Predictive factor for the response to adjuvant therapy with emphasis in breast cancer.
1/2000An immunotherapeutic approach to treatment of breast cancer: focus on trastuzumab plus paclitaxel. Breast Cancer Medicine Service.
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L Norton Research Topics

Disease

33Breast Neoplasms (Breast Cancer)
01/2016 - 01/2000
27Neoplasms (Cancer)
11/2018 - 01/2000
7Neoplasm Metastasis (Metastasis)
08/2015 - 02/2000
5Type 2 Diabetes Mellitus (MODY)
05/2016 - 03/2007
5Leukemia
12/2005 - 03/2000
4Insulin Resistance
03/2008 - 01/2007
2Carcinoma (Carcinomatosis)
06/2014 - 04/2001
2Fatigue
12/2011 - 04/2001
2Diarrhea
12/2011 - 04/2001
2Type 1 Diabetes Mellitus (Autoimmune Diabetes)
09/2007 - 02/2007
2Cardiotoxicity
12/2005 - 01/2000
2Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
05/2005 - 04/2001
2Osteoporosis
12/2001 - 01/2001
2Disease Progression
03/2001 - 02/2000
1Cardiovascular Diseases (Cardiovascular Disease)
05/2016
1Myocardial Infarction
05/2016
1Stroke (Strokes)
05/2016
1Lobular Carcinoma
01/2014
1Pancreatitis
03/2013
1Inflammation (Inflammations)
09/2012
1Wounds and Injuries (Trauma)
09/2012
1Infections
09/2012
1Exanthema (Rash)
12/2011
1Coma (Comas)
11/2008
1Heart Arrest (Cardiac Arrest)
11/2008
1Overweight
07/2007
1Starvation
03/2007
1Necrosis
01/2006
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2005
1Non-Hodgkin Lymphoma (Lymphosarcoma)
05/2005
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
10/2004
1Lymphoma (Lymphomas)
10/2004

Drug/Important Bio-Agent (IBA)

8Proteins (Proteins, Gene)FDA Link
01/2010 - 01/2000
7Paclitaxel (Taxol)FDA LinkGeneric
01/2016 - 01/2000
7Doxorubicin (Adriamycin)FDA LinkGeneric
02/2009 - 01/2000
6Trastuzumab (Herceptin)FDA Link
01/2016 - 01/2000
6Cyclophosphamide (Cytoxan)FDA LinkGeneric
02/2009 - 01/2000
4Estrogen ReceptorsIBA
01/2014 - 10/2000
4Selective Estrogen Receptor Modulators (SERM)IBA
09/2008 - 01/2001
3Fluorouracil (Carac)FDA LinkGeneric
02/2009 - 10/2000
3Raloxifene Hydrochloride (Evista)FDA Link
09/2008 - 01/2001
3Insulin (Novolin)FDA Link
09/2007 - 02/2007
3AntibodiesIBA
01/2006 - 03/2001
3Monoclonal AntibodiesIBA
03/2001 - 01/2000
2Circulating Tumor DNAIBA
11/2018 - 01/2014
2ErbB Receptors (EGF Receptor)IBA
01/2016 - 02/2000
2N,N'-bis(4-azidobenzoyl)cystineIBA
10/2014 - 10/2014
2Cadherins (E-Cadherin)IBA
06/2014 - 02/2000
2DNA (Deoxyribonucleic Acid)IBA
01/2014 - 11/2000
2Methotrexate (Mexate)FDA LinkGeneric
02/2009 - 04/2001
2Messenger RNA (mRNA)IBA
03/2008 - 07/2007
2Blood Glucose (Blood Sugar)IBA
09/2007 - 02/2007
2CarbohydratesIBA
03/2007 - 03/2001
2Glucose (Dextrose)FDA LinkGeneric
02/2007 - 01/2007
2GlycogenIBA
02/2007 - 01/2007
2AnthracyclinesIBA
12/2005 - 04/2001
2TamoxifenFDA LinkGeneric
12/2001 - 10/2000
2Immunoglobulin M (IgM)IBA
03/2001 - 05/2000
2Immunoglobulin G (IgG)IBA
03/2001 - 05/2000
1Pioglitazone (Actos)FDA Link
05/2016
1empagliflozinIBA
05/2016
1omega-Chloroacetophenone (Mace)IBA
05/2016
1pertuzumabIBA
01/2016
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
06/2014
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
06/2014
1Isoniazid (Ftivazide)FDA LinkGeneric
03/2013
1Dasatinib (BMS 354825)FDA Link
12/2011
1Transcription Factors (Transcription Factor)IBA
12/2011
1Taxoids (Taxanes)IBA
12/2011
1Capecitabine (Xeloda)FDA Link
11/2010
1Hormones (Hormone)IBA
09/2008
1exemestane (Aromasin)FDA Link
09/2008
1Aromatase InhibitorsIBA
09/2008
1Letrozole (Femara)FDA LinkGeneric
05/2008
1LipidsIBA
03/2008
1Liver GlycogenIBA
09/2007
1Fatty Acid-Binding ProteinsIBA
07/2007
1Fatty Acid Transport Proteins (Fatty Acid Transport Protein)IBA
07/2007
1Fatty Acids (Saturated Fatty Acids)IBA
07/2007
1LigandsIBA
01/2006
1Mitoxantrone (Novantrone)FDA LinkGeneric
12/2005
1Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric
05/2005
1Prednisone (Sone)FDA LinkGeneric
10/2004
1Vincristine (Oncovin)FDA LinkGeneric
10/2004
1Leucovorin (Folinic Acid)FDA Link
05/2003
1Anticarcinogenic AgentsIBA
12/2001
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
09/2001
1Progesterone Receptors (Progesterone Receptor)IBA
09/2001
1Macrocyclic LactamsIBA
08/2001
1tanespimycin (17AAG)IBA
08/2001

Therapy/Procedure

11Therapeutics
08/2015 - 01/2000
10Drug Therapy (Chemotherapy)
12/2005 - 01/2000
5Adjuvant Chemotherapy
12/2001 - 03/2000
1Debridement
09/2012
1Radiotherapy
02/2009
1Mastectomy (Mammectomy)
02/2009
1Resuscitation
11/2008
1Induced Hypothermia
11/2008
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
12/2005
1CAV protocol
10/2004